Description
ATP5H is the 'd' subunit of Mitochondrial ATP synthase complex which catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. The ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo has nine known subunits (a, b, c, d, e, f, g, F6 and 8). The ATP5H gene encodes the d subunit of the Fo complex